serotonin

noun

se·​ro·​to·​nin ˌsir-ə-ˈtō-nən How to pronounce serotonin (audio)
ˌser-
: a phenolic amine neurotransmitter C10H12N2O that is a powerful vasoconstrictor and is found especially in the brain, blood serum, and gastric mucous membrane of mammals

Examples of serotonin in a Sentence

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Tryptophan is an amino acid needed to make melatonin and serotonin, which control sleep. Johna Burdeos, Health, 8 Apr. 2025 Similarly, cortisol and serotonin levels are lowered — which can respectively result in lower stress and greater levels of obsession. Mark Travers, Forbes.com, 7 Apr. 2025 Little Kitty, Big City Any subscription service needs to feature a few jolts of serotonin that are quick to download and easy to please, and right now, the reigning champion in the field is undoubtedly Little Kitty, Big City. Luke Winkie, Vulture, 1 Apr. 2025 People who regularly ate citrus were shown to have beneficial gut bacteria that may boost the production of serotonin and dopamine. Emily Kay Votruba, EverydayHealth.com, 28 Feb. 2025 See All Example Sentences for serotonin

Word History

Etymology

sero- + ton(ic) entry 2 or tone entry 1 + -in entry 1, probably after angiotonin, earlier name for angiotensin — more at angiotensin

Note: Term introduced by Maurice M. Rapport, Arda Alden Green and Irvine H. Page in "Crystalline serotonin," Science, vol. 108, Issue 2804 (September 24, 1948), pp. 329-330: "The general behavior of the crystalline substance is suggestive of its homogeneity. We would like provisionally to name it serotonin, which indicates that its source is serum and its activity is one of causing constriction."

First Known Use

1948, in the meaning defined above

Time Traveler
The first known use of serotonin was in 1948

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Cite this Entry

“Serotonin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/serotonin. Accessed 21 Apr. 2025.

Medical Definition

serotonin

noun
se·​ro·​to·​nin ˌsir-ə-ˈtō-nən How to pronounce serotonin (audio) ˌser- How to pronounce serotonin (audio)
: a phenolic amine neurotransmitter C10H12N2O that is a powerful vasoconstrictor and is found especially in the brain, blood serum, and gastric mucous membrane of mammals

called also 5-HT, 5-hydroxytryptamine

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