1
: any of several diseases characterized by skin lesions
especially
: systemic lupus erythematosus sense 2
2
Lupus astronomy
: a southern constellation that is visible between the constellations of Scorpius and Centaurus and that is represented by the figure of a wolf
Above Lupus lies Scorpius, one of the few constellations whose star pattern actually suggests the object that it is named for. In the myths, the scorpion was assigned by Artemis, the hunting goddess, to kill Orion, far across the sky.—
Don Moser
Don MoserExamples of lupus in a Sentence
Recent Examples on the Web
This includes conditions like Hashimoto’s thyroiditis, lupus and rheumatoid arthritis.
—Elizabeth Yuko, Flow Space, 23 July 2025
Efforts are also underway to teach residents how to safely live with the most recent wild arrivals—Apennine wolves (Canis lupus italicus).
—Krista Langlois, Smithsonian Magazine, 7 July 2025
Weight loss can also happen, especially if lupus affects your digestive system or appetite.
—Stella Bard, Health, 27 June 2025
Rheumatic diseases, such as rheumatoid arthritis, lupus and scleroderma, are chronic conditions that affect joints, muscles and connective tissue.
—Chloe Castleberry, Flow Space, 7 July 2025
See All Example Sentences for lupus
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Elizabeth Yuko, Flow Space, 23 July 2025
Efforts are also underway to teach residents how to safely live with the most recent wild arrivals—Apennine wolves (Canis lupus italicus).
—Krista Langlois, Smithsonian Magazine, 7 July 2025
Weight loss can also happen, especially if lupus affects your digestive system or appetite.
—Stella Bard, Health, 27 June 2025
Rheumatic diseases, such as rheumatoid arthritis, lupus and scleroderma, are chronic conditions that affect joints, muscles and connective tissue.
—Chloe Castleberry, Flow Space, 7 July 2025
See All Example Sentences for lupus
Cite this Entry
“Lupus.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/lupus. Accessed 30 Jul. 2025.
Copy CitationMedical Definition
lupus
noun
lu·pus
ˈlü-pəs 
: any of several diseases (as lupus vulgaris or systemic lupus erythematosus) characterized by skin lesions
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