leptin

noun

lep·​tin ˈlep-tən How to pronounce leptin (audio)
: a peptide hormone that is produced by fat cells and plays a role in body weight regulation by acting on the hypothalamus to suppress appetite and burn fat stored in adipose tissue

Examples of leptin in a Sentence

Recent Examples on the Web
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When dieting or losing weight, ghrelin levels tend to rise while leptin levels typically decrease.13 Essentially, ghrelin and leptin work together to control your appetite by sending hunger and satiety cues. Brittany Lubeck, Ms, Rdn, Verywell Health, 14 Apr. 2025 Their nutrient profile also helps regulate appetite hormones like ghrelin and leptin, which control hunger and satiety. 4. Bryan Robinson, Forbes.com, 7 Apr. 2025 Exercise can help balance leptin and ghrelin, hormones involved in hunger, energy balance, and sleep. Wendy Wisner, Health, 31 Mar. 2025 Ghrelin, an appetite stimulant, rises when you are sleep-deprived, and leptin decreases. Judy Stone, Forbes, 10 Mar. 2025 See All Example Sentences for leptin

Word History

Etymology

Greek leptos slender + English -in entry 1

First Known Use

1995, in the meaning defined above

Time Traveler
The first known use of leptin was in 1995

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Cite this Entry

“Leptin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/leptin. Accessed 21 Apr. 2025.

Medical Definition

leptin

noun
lep·​tin ˈlep-tən How to pronounce leptin (audio)
: a peptide hormone that is produced by fat cells and plays a role in body weight regulation by acting on the hypothalamus to suppress appetite and burn fat stored in adipose tissue

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