intolerance

noun

in·​tol·​er·​ance (ˌ)in-ˈtä-lə-rən(t)s How to pronounce intolerance (audio)
-ˈtäl-rən(t)s
1
: the quality or state of being intolerant
2
: exceptional sensitivity (as to a drug)
specifically : inability to properly metabolize or absorb a substance

Examples of intolerance in a Sentence

a group whose mission is to oppose intolerance and extremism
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Ethanol or acetaldehyde sensitivity In people with alcohol intolerance, the body lacks the enzyme ALDH2 needed to break down acetaldehyde, a toxic byproduct of alcohol metabolism. Lauryn Higgins, Time, 22 July 2025 For people with serious lactose intolerance, eating a heavily cheesy meal before bed could lead to bad dreams and sleep disturbances, a new study found. Kaylah Jackson, NBC news, 1 July 2025 Key Takeaways New research suggests lactose intolerance can cause nightmares, possibly because of symptoms like stomachache that disrupt sleep. Emily Kay Votruba, EverydayHealth.com, 1 July 2025 Taken together, the researchers’ results indicated that lactose intolerance was related to nighttime gastrointestinal discomfort, poor sleep, and nightmares. Sam Walters, Discover Magazine, 1 July 2025 See All Example Sentences for intolerance

Word History

First Known Use

1765, in the meaning defined at sense 1

Time Traveler
The first known use of intolerance was in 1765

Browse Nearby Words

Cite this Entry

“Intolerance.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/intolerance. Accessed 29 Jul. 2025.

Kids Definition

intolerance

noun
in·​tol·​er·​ance (ˈ)in-ˈtäl-(ə-)rən(t)s How to pronounce intolerance (audio)
1
: the quality or state of being intolerant
2
: exceptional sensitivity (as to a drug or food)

Medical Definition

intolerance

noun
in·​tol·​er·​ance (ˈ)in-ˈtäl(-ə)-rən(t)s How to pronounce intolerance (audio)
1
: lack of an ability to endure
an intolerance to light
2
: exceptional sensitivity (as to a food or drug)
specifically : inability to properly metabolize or absorb a substance
glucose intolerance

More from Merriam-Webster on intolerance

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!