insulin-like growth factor

noun

in·​su·​lin-like growth factor ˈin(t)-s(ə-)lən-ˈlīk- How to pronounce insulin-like growth factor (audio)
: either of two polypeptides structurally similar to insulin that are secreted either during fetal development or during childhood and that mediate growth hormone activity

Examples of insulin-like growth factor in a Sentence

Recent Examples on the Web
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People who take a GLP-1 medication also tend to have elevated levels of insulin-like growth factor 1 (IGF-1), a growth hormone that helps control sebum production. Claire Bugos, Verywell Health, 10 Apr. 2025 During childhood, hormones—including thyroid hormones, human growth hormone (HGH), and insulin-like growth factor 1—play a major role in healthy growth and development. Laura Dorwart, Verywell Health, 2 Jan. 2025 These peptides, in turn, activate the insulin-like growth factor 1 (IGF-1) signaling pathway in NSCs and triggers their reactivation. New Atlas, 15 Aug. 2024 Researchers are unsure exactly why dairy causes acne, but some evidence suggests that milk raises insulin-like growth factor 1 (IGF-1) levels, which increases sebum (oil) production. Kathleen Felton, Health, 11 Sep. 2023 Laron syndrome results from a mutation in the gene that codes for growth hormone receptor (GHR), a protein that binds with the human growth hormone and ultimately results in the production of the insulin-like growth factor 1 (IGF1), causing cells to grow and divide. Andrew Moseman, Discover Magazine, 17 Feb. 2011 In 1956 Daughaday discovered the hormone now called insulin-like growth factor 1, or IGF-1. Gary Taubes, Discover Magazine, 26 Mar. 2013 As animals grow, two proteins play a major role: insulin and insulin-like growth factor (known as IGF). Carl Zimmer, Discover Magazine, 26 July 2012 Fueling all these promises is a hormone called IGF-1 (short for insulin-like growth factor). Elizabeth Preston, Discover Magazine, 28 Feb. 2013

Word History

First Known Use

1976, in the meaning defined above

Time Traveler
The first known use of insulin-like growth factor was in 1976

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Cite this Entry

“Insulin-like growth factor.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/insulin-like%20growth%20factor. Accessed 19 Apr. 2025.

Medical Definition

insulin-like growth factor

noun
in·​su·​lin-like growth factor ˌin(t)-s(ə-)lən-ˌlīk- How to pronounce insulin-like growth factor (audio)
: either of two polypeptides structurally similar to insulin that are secreted either during fetal development or during childhood and that mediate growth hormone activity
Last Updated: - Updated example sentences
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