haplotype

noun

hap·​lo·​type ˈha-plō-ˌtīp How to pronounce haplotype (audio)
: a group of alleles of different genes (as of the major histocompatibility complex) on a single chromosome that are closely enough linked to be inherited usually as a unit

Examples of haplotype in a Sentence

Recent Examples on the Web
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Analysis of ancient and modern human genomes, along with those of our closest relatives, revealed a common haplotype, or group of alleles (different forms of a gene), inherited together from one parent. Elizabeth Rayne, Ars Technica, 27 Dec. 2024 This haplotype has three copies of AMY1 and was present in samples that predated our migration out of Africa. Elizabeth Rayne, Ars Technica, 27 Dec. 2024 Specific combinations of these mutations—called a haplotype—seem to confer a higher risk of developing type 1 diabetes. Amanda Gardner, Health, 20 Nov. 2023 In the absence of allelic competitors this variant sweeps up in frequency extremely rapidly, and flanking regions of the genome generate a long haplotype block. Razib Khan, Discover Magazine, 13 Sep. 2013 See All Example Sentences for haplotype

Word History

First Known Use

1967, in the meaning defined above

Time Traveler
The first known use of haplotype was in 1967

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Cite this Entry

“Haplotype.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/haplotype. Accessed 30 Jul. 2025.

Medical Definition

haplotype

noun
hap·​lo·​type -ˌtīp How to pronounce haplotype (audio)
: a group of alleles of different genes (as of the major histocompatibility complex) on a single chromosome that are closely enough linked to be inherited usually as a unit

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