: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases (see base entry 1 sense 6b) which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei compare recombinant dna

Illustration of DNA

Illustration of dna
  • A molecular model
  • 1 hydrogen
  • 2 oxygen
  • 3 carbon in the helical phosphate ester chains
  • 4 carbon and nitrogen in the cross-linked purine and pyrimidine bases
  • 5 phosphorus
  • B double helix

Examples of DNA in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The project entailed extracting environmental DNA from river water and examining it for the presence of invasive silver and bighead carp. Madeline Heim, jsonline.com, 24 July 2025 The concept, however, is the same – scientists are banding together to do more innovative work on cell structure, for example, in nucleus and mitochondria DNA. John Werner, Forbes.com, 24 July 2025 According to the probable cause affidavit reviewed by PEOPLE in January 2023, authorities identified him after matching DNA on trash taken from Bryan's parents' home to that of the sheath of the knife used in the stabbings that was left at the crime scene. Jordana Comiter, People.com, 24 July 2025 For instance, the biomedicine AI start-up Arc Institute is designing a machine learning model trained on DNA of 100,000 species to identify disease-causing genome mutations and to assist new drug discovery. Gerui Wang, Forbes.com, 12 July 2025 See All Example Sentences for DNA

Word History

Etymology

deoxyribonucleic acid

First Known Use

1944, in the meaning defined above

Time Traveler
The first known use of DNA was in 1944

Browse Nearby Words

Cite this Entry

“DNA.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/DNA. Accessed 29 Jul. 2025.

Kids Definition

: any of various nucleic acids that are located especially in cell nuclei, are usually the chemical basis of heredity, and are composed of two nucleotide chains held together by hydrogen bonds in a pattern resembling a flexible twisted ladder compare rna

Medical Definition

: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei

called also deoxyribonucleic acid

see recombinant dna

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