differentiation

noun

dif·​fer·​en·​ti·​a·​tion ˌdi-fə-ˌren(t)-shē-ˈā-shən How to pronounce differentiation (audio)
1
: the act or process of differentiating
2
: development from the one to the many, the simple to the complex, or the homogeneous to the heterogeneous
differentiation of Latin into vernaculars
3
biology
a
: modification of body parts for performance of particular functions
b
: the sum of the processes whereby apparently indifferent (see indifferent sense 7) or unspecialized cells, tissues, and structures attain their adult form and function
4
geology : the processes by which various rock types are produced from a common magma

Examples of differentiation in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Scalable Growth And Competitive Differentiation One effective strategy to increase venture capital investment in your business is to demonstrate a clear path to scalable growth with defensible market differentiation. Expert Panel®, Forbes.com, 25 July 2025 Wnt signals help maintain a balance between stem cell self-renewal (keeping enough stem cells in the crypts) and differentiation (turning some stem cells into specialized cells that make up the lining of the intestine). New Atlas, 24 July 2025 These are still critical ingredients to creating differentiation and competitive advantage. Fortune Editors, Fortune, 23 July 2025 That’s because the equations rely on a technique from calculus called differentiation that measures how quickly functions change, and differentiation is no longer possible in settings that are far from smooth. Quanta Magazine, 16 July 2025 See All Example Sentences for differentiation

Word History

Etymology

borrowed from New Latin differentiātiōn-, differentiātiō, from Medieval Latin differentiāre "to distinguish, differentiate" + Latin -tiōn-, -tiō, suffix of verbal action

First Known Use

1776, in the meaning defined at sense 1

Time Traveler
The first known use of differentiation was in 1776

Browse Nearby Words

Cite this Entry

“Differentiation.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/differentiation. Accessed 29 Jul. 2025.

Kids Definition

differentiation

noun
dif·​fer·​en·​ti·​a·​tion ˌdif-ə-ˌren-chē-ˈā-shən How to pronounce differentiation (audio)
1
: the act or process of differentiating
2
: the processes by which cells and tissues develop their specialized adult form and function
also : the result of these processes

Medical Definition

differentiation

noun
dif·​fer·​en·​ti·​a·​tion -ˌren-chē-ˈā-shən How to pronounce differentiation (audio)
1
a
: the act of describing a thing by giving its differentia
b
: the enhancement of microscopically visible differences between tissue or cell parts by partial selective decolorization or removal of excess stain (as in regressive staining)
c
: the development of a discriminating conditioned response with a positive response to one stimulus and absence of the response on the application of similar but discriminably different stimuli
2
a
: modification of different parts of the body for performance of particular functions
also : specialization of parts or organs in the course of evolution
b
: the sum of the developmental processes whereby apparently unspecialized cells, tissues, and structures attain their adult form and function compare determination sense 2
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