ceramide

noun

cer·​amide ˈsir-ə-ˌmīd How to pronounce ceramide (audio)
ˈser-
plural ceramides
: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids
The enzyme controls production of a cellular substance, ceramide, which triggers the natural process of egg cell death.L. Stivitz
Moisturizers containing ceramides (natural lipids that are similar in structure to those in the skin's own moisture barrier) … are also worthwhile splurges for women with dry or problem skin, according to independent tester Grove.Constance Cardozo

Examples of ceramide in a Sentence

Recent Examples on the Web
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First Aid Beauty’s version prioritizes moisture with a potent combo of squalane and ceramides. Deanna Pai, Glamour, 28 May 2025 Lucky for you, our editors sniffed through their stashes to round up shampoos and conditioners that marry top-tier efficacy (think skin- and hair-loving ingredients like hyaluronic acid, peptides, ceramides, and botanical blends) with both luxe and lightweight fragrance notes. Annie Blackman, Allure, 25 May 2025 Its second task is to provide long-term and ongoing resilience by sending biomimetic peptides and skin-identical ceramides deep into the dermis for firmness and a clear complexion. Justin Fenner, Robb Report, 12 May 2025 Not to mention, it’s packed with peptides, ceramides, hyaluronic acid, allantoin to keep your complexion fresh, nourished, and calm. Kiana Murden, Vogue, 2 May 2025 See All Example Sentences for ceramide

Word History

Etymology

cerebroside + amide

First Known Use

1958, in the meaning defined above

Time Traveler
The first known use of ceramide was in 1958

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Cite this Entry

“Ceramide.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/ceramide. Accessed 9 Jun. 2025.

Medical Definition

ceramide

noun
cer·​amide ˈsir-ə-ˌmīd How to pronounce ceramide (audio)
: any of a group of amido sphingolipids formed by linking a fatty acid to sphingosine and found widely in small amounts in plant and animal tissue

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